Biomechanical Imaging and Computation Lab

The Biomechanical Imaging and Computation Lab develops tools for multi-parameter and multiscale mapping of tissue mechanical environment for early detection of fibrosis and cancer, as well as advancement of our understanding of the interaction between pathology and its biomechanical environment. Our work covers fundamental and translational research in elastography from macro-scale magnetic resonance elastography/ ultrasound elastography to microscale optical coherence elastography.

We work highly collaboratively at the intersection of engineering, physics, and biology. In short, in our laboratory, we are:

  1. Developing computational, optimization, and AI-driven algorithms for fast acquisition and reliable reconstruction of elastography for clinical diagnosis
  2. Developing a multiscale multiparametric elastography system with multimodality imaging to advance understanding of tissue biomechanics and pathogenesis.
  3. Exploring the possibility of a biomechanics-informed patient-specific digital twin for health management
  4. Translating elastography techniques to new clinical applications in pulmonary, hepatology, urology, cardiology, and reproductive medicine.

We welcome graduate and undergraduate students interested in our work to join our lab. We are open to collaborations with other labs in Charlotte and North Carolina! Please reach out if you are interested in applying elastography in cancer and fibrosis detection, advanced dynamic imaging and reconstruction in medical imaging, or understanding the interplay between pathogenesis and biomechanics from an engineering perspective.