The William States Lee College of Engineering



– Choi EH, Nwakalor C, Brown NJ, Lee J, Oh MY, Yang IH. Therapeutic potential of neuromodulation for demyelinating diseases. Neural Regen Res2021 Feb;16(2):214-217doi: 10.4103/1673-5374.290876. Review. PubMed PMID: 32859766; PubMed Central PMCID: PMC7896214.
– Choi EH, Blasiak A, Lee J, Yang IH. Modulation of Neural Activity for Myelination in the Central Nervous System. Front Neurosci2019;13:952doi: 10.3389/fnins.2019.00952. eCollection 2019. Review. PubMed PMID: 31555087; PubMed Central PMCID: PMC6742708.
– Zeng X, Chen S, Weitemier A, Han S, Blasiak A, Prasad A, Zheng K, Yi Z, Luo B, Yang IH, Thakor N, Chai C, Lim KL, McHugh TJ, All AH, Liu X. Visualization of Intra-neuronal Motor Protein Transport through Upconversion Microscopy. Angew Chem Int Ed Engl2019 Jul 1;58(27):9262-9268doi: 10.1002/anie.201904208. Epub 2019 May 28. PubMed PMID: 31087740.
– Blasiak A, Guerin THM, Teh DBL, Yang IH, Lahiri A, Thakor NV. Fibro-Neuronal Guidance on Common, 3D-Printed Textured Substrates. IEEE Trans Nanobioscience2019 Apr;18(2):226-229doi: 10.1109/TNB.2019.2905469. Epub 2019 Mar 15. PubMed PMID: 30892222.
– Luo B, Tian L, Chen N, Ramakrishna S, Thakor N, Yang IH. Electrospun nanofibers facilitate better alignment, differentiation, and long-term culture in an in vitro model of the neuromuscular junction (NMJ). Biomater Sci2018 Nov 20;6(12):3262-3272doi: 10.1039/c8bm00720a. PubMed PMID: 30402630.
– Wang J, Tian L, Luo B, Ramakrishna S, Kai D, Loh XJ, Yang IH, Deen GR, Mo X. Engineering PCL/lignin nanofibers as an antioxidant scaffold for the growth of neuron and Schwann cell. Colloids Surf B Biointerfaces2018 Sep 1;169:356-365doi: 10.1016/j.colsurfb.2018.05.021. Epub 2018 May 12. PubMed PMID: 29803151.
– Blasiak A, Nag S, Yang IH. Subcellular Optogenetic Stimulation Platform for Studying Activity-Dependent Axon Myelination In Vitro. Methods Mol Biol2018;1791:207-224doi: 10.1007/978-1-4939-7862-5_16. PubMed PMID: 30006712.
– Prasad A, Teh DBL, Blasiak A, Chai C, Wu Y, Gharibani PM, Yang IH, Phan TT, Lim KL, Yang H, Liu X, All AH. Static Magnetic Field Stimulation Enhances Oligodendrocyte Differentiation and Secretion of Neurotrophic Factors. Sci Rep2017 Jul 27;7(1):6743doi: 10.1038/s41598-017-06331-8. PubMed PMID: 28751716; PubMed Central PMCID: PMC5532210.
– Lee HU, Blasiak A, Agrawal DR, Loong DTB, Thakor NV, All AH, Ho JS, Yang IH. Subcellular electrical stimulation of neurons enhances the myelination of axons by oligodendrocytes. PLoS One2017;12(7):e0179642doi: 10.1371/journal.pone.0179642. eCollection 2017. PubMed PMID: 28671962; PubMed Central PMCID: PMC5495216.
– Sinha S, Fu YY, Grimont A, Ketcham M, Lafaro K, Saglimbeni JA, Askan G, Bailey JM, Melchor JP, Zhong Y, Joo MG, Grbovic-Huezo O, Yang IH, Basturk O, Baker L, Park Y, Kurtz RC, Tuveson D, Leach SD, Pasricha PJ. PanIN Neuroendocrine Cells Promote Tumorigenesis via Neuronal Cross-talk. Cancer Res2017 Apr 15;77(8):1868-1879doi: 10.1158/0008-5472.CAN-16-0899-T. Epub 2017 Apr 6. PubMed PMID: 28386018; PubMed Central PMCID: PMC5471615.
– Lee HU, Nag S, Blasiak A, Jin Y, Thakor N, Yang IH. Subcellular Optogenetic Stimulation for Activity-Dependent Myelination of Axons in a Novel Microfluidic Compartmentalized Platform. ACS Chem Neurosci2016 Oct 19;7(10):1317-1324doi: 10.1021/acschemneuro.6b00157. Epub 2016 Sep 13. PubMed PMID: 27570883.
– Cetinkaya-Fisgin A, Joo MG, Ping X, Thakor NV, Ozturk C, Hoke A, Yang IH. Identification of fluocinolone acetonide to prevent paclitaxel-induced peripheral neuropathy. J Peripher Nerv Syst2016 Sep;21(3):128-33doi: 10.1111/jns.12172. PubMed PMID: 27117347.
– Zhang P, Abdelmohsen K, Liu Y, Tominaga-Yamanaka K, Yoon JH, Ioannis G, Martindale JL, Zhang Y, Becker KG, Yang IH, Gorospe M, Mattson MP. Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity. Nat Commun2015 Nov 20;6:8888doi: 10.1038/ncomms9888. PubMed PMID: 26586091; PubMed Central PMCID: PMC4673492.
– Markus A, Lebenthal-Loinger I, Yang IH, Kinchington PR, Goldstein RS. An in vitro model of latency and reactivation of varicella zoster virus in human stem cell-derived neurons. PLoS Pathog2015 Jun;11(6):e1004885doi: 10.1371/journal.ppat.1004885. eCollection 2015 Jun. PubMed PMID: 26042814; PubMed Central PMCID: PMC4456082.
– Grigoryan S, Yee MB, Glick Y, Gerber D, Kepten E, Garini Y, Yang IH, Kinchington PR, Goldstein RS. Direct transfer of viral and cellular proteins from varicella-zoster virus-infected non-neuronal cells to human axons. PLoS One2015;10(5):e0126081doi: 10.1371/journal.pone.0126081. eCollection 2015. PubMed PMID: 25973990; PubMed Central PMCID: PMC4431828.
– Malone M, Gary D, Yang IH, Miglioretti A, Houdayer T, Thakor N, McDonald J. Neuronal activity promotes myelination via a cAMP pathway. Glia2013 Jun;61(6):843-54doi: 10.1002/glia.22476. Epub 2013 Mar 28. PubMed PMID: 23554117.
– Park HS, Liu S, McDonald J, Thakor N, Yang IH. Neuromuscular junction in a microfluidic device. Annu Int Conf IEEE Eng Med Biol Soc2013;2013:2833-5doi: 10.1109/EMBC.2013.6610130. PubMed PMID: 24110317.
– Grigoryan S, Kinchington PR, Yang IH, Selariu A, Zhu H, Yee M, Goldstein RS. Retrograde axonal transport of VZV: kinetic studies in hESC-derived neurons. J Neurovirol2012 Dec;18(6):462-70doi: 10.1007/s13365-012-0124-z. Epub 2012 Aug 24. PubMed PMID: 22918852; PubMed Central PMCID: PMC3556991.
– Wang T, Lee MH, Choi E, Pardo-Villamizar CA, Lee SB, Yang IH, Calabresi PA, Nath A. Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel. PLoS One2012;7(8):e43950doi: 10.1371/journal.pone.0043950. Epub 2012 Aug 29. PubMed PMID: 22952817; PubMed Central PMCID: PMC3430617.
– Yang IH, Gary D, Malone M, Dria S, Houdayer T, Belegu V, McDonald JW, Thakor N. Axon myelination and electrical stimulation in a microfluidic, compartmentalized cell culture platform. Neuromolecular Med2012 Jun;14(2):112-8doi: 10.1007/s12017-012-8170-5. Epub 2012 Apr 13. PubMed PMID: 22527791.
– Hosmane S, Fournier A, Wright R, Rajbhandari L, Siddique R, Yang IH, Ramesh KT, Venkatesan A, Thakor N. Valve-based microfluidic compression platform: single axon injury and regrowth. Lab Chip2011 Nov 21;11(22):3888-95doi: 10.1039/c1lc20549h. Epub 2011 Oct 6. PubMed PMID: 21975691.
– Markus A, Grigoryan S, Sloutskin A, Yee MB, Zhu H, Yang IH, Thakor NV, Sarid R, Kinchington PR, Goldstein RS. Varicella-zoster virus (VZV) infection of neurons derived from human embryonic stem cells: direct demonstration of axonal infection, transport of VZV, and productive neuronal infection. J Virol2011 Jul;85(13):6220-33doi: 10.1128/JVI.02396-10. Epub 2011 Apr 27. PubMed PMID: 21525353; PubMed Central PMCID: PMC3126485.
– Yang IH, Co CC, Ho CC. Controlling neurite outgrowth with patterned substrates. J Biomed Mater Res A2011 Jun 15;97(4):451-6doi: 10.1002/jbm.a.33082. Epub 2011 Apr 11. PubMed PMID: 21484989; PubMed Central PMCID: PMC3088767.
– Ziegler L, Grigoryan S, Yang IH, Thakor NV, Goldstein RS. Efficient generation of schwann cells from human embryonic stem cell-derived neurospheres. Stem Cell Rev Rep2011 Jun;7(2):394-403doi: 10.1007/s12015-010-9198-2. PubMed PMID: 21052870.
– Hur EM, Yang IH, Kim DH, Byun J, Saijilafu, Xu WL, Nicovich PR, Cheong R, Levchenko A, Thakor N, Zhou FQ. Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. Proc Natl Acad Sci U S A2011 Mar 22;108(12):5057-62doi: 10.1073/pnas.1011258108. Epub 2011 Mar 7. PubMed PMID: 21383151; PubMed Central PMCID: PMC3064397.
– Keshet B, Yang IH, Good TA. Can size alone explain some of the differences in toxicity between beta-amyloid oligomers and fibrils?. Biotechnol Bioeng2010 Jun 1;106(2):333-7doi: 10.1002/bit.22691. PubMed PMID: 20148403; PubMed Central PMCID: PMC2935630.
– Hosmane S, Yang IH, Ruffin A, Thakor N, Venkatesan A. Circular compartmentalized microfluidic platform: Study of axon-glia interactions. Lab Chip2010 Mar 21;10(6):741-7doi: 10.1039/b918640a. Epub 2010 Jan 5. PubMed PMID: 20221562.
– Yang IH, Siddique R, Hosmane S, Thakor N, Höke A. Compartmentalized microfluidic culture platform to study mechanism of paclitaxel-induced axonal degeneration. Exp Neurol2009 Jul;218(1):124-8doi: 10.1016/j.expneurol.2009.04.017. Epub 2009 May 3. PubMed PMID: 19409381; PubMed Central PMCID: PMC4440669.
– Yang IH, Lee D, Lee SH, Kang JY. Characterization of proteolytically digested zebrafish chorion as extracellular matrix. Annu Int Conf IEEE Eng Med Biol Soc2008;2008:1837-40doi: 10.1109/IEMBS.2008.4649537. PubMed PMID: 19163040.
– Yang IH, Co CC, Ho CC. Spatially controlled co-culture of neurons and glial cells. J Biomed Mater Res A2005 Dec 15;75(4):976-84doi: 10.1002/jbm.a.30509. PubMed PMID: 16138329.
– Yang IH, Co CC, Ho CC. Alteration of human neuroblastoma cell morphology and neurite extension with micropatterns. Biomaterials2005 Nov;26(33):6599-609doi: 10.1016/j.biomaterials.2005.04.024. PubMed PMID: 15936072.