{"id":46,"date":"2026-03-17T21:15:59","date_gmt":"2026-03-18T01:15:59","guid":{"rendered":"https:\/\/coefs.charlotte.edu\/agaitas\/?page_id=46"},"modified":"2026-03-18T11:56:50","modified_gmt":"2026-03-18T15:56:50","slug":"publications-and-patents","status":"publish","type":"page","link":"https:\/\/coefs.charlotte.edu\/agaitas\/publications-and-patents\/","title":{"rendered":"Publications and Patents"},"content":{"rendered":"\n

Peer-Reviewed Journal Articles<\/strong><\/h2>\n\n\n\n

Patel, Vishwendra, Onnop Srivannavit, Irene C. Turnbull, Robert Blitzer, and Angelo Gaitas. “Micromachined Thermocouple Microprobe for Real-Time Thermometry of Hippocampal Slices during High-Frequency Stimulation.” (2026, under review)<\/p>\n\n\n\n

Turnbull, Irene C., Tai De Li, Pedro Sanabria, Aimee Stablewski, and Angelo Gaitas. “Non-invasive biomechanical characterization of embryos using microfluidic cantilevers.” European Biophysics Journal (2026): 1-8.<\/p>\n\n\n\n

Turnbull, I.C., Gaitas, A. “Characterizing Induced Pluripotent Stem Cells and Derived Cardiomyocytes: Insights from Nano Scale Mass Measurements and Mechanical Properties.” Nanoscale Advances (2024).<\/p>\n\n\n\n

Srivannavit, O., Joshi, R., Zhu, W., Gong, B., Turnbull, I.C., Patel, V., Sealfon, S.C., Borca-Tasciuc, T., Blitzer, R.D., Gaitas, A. “Design, fabrication, and calibration of a micromachined thermocouple for biological applications in temperature monitoring.” Biosensors and Bioelectronics (2024).<\/p>\n\n\n\n

Turnbull, I.C., Bajpai, A., Jankowski, K.B., and Gaitas, A. “Single-Cell Analysis of Contractile Forces in iPSC-Derived Cardiomyocytes: Paving the Way for Precision Medicine in Cardiovascular Disease.” International Journal of Molecular Sciences 24(17), p.13416 (2023).<\/p>\n\n\n\n

Bei, J., Miranda-Morales, E.G., Gan, Q., Qiu, Y., Husseinzadeh, S., Liew, J.Y., Chang, Q., Krishnan, B., Gaitas, A., Yuan, S., Felicella, M. “Circulating exosomes from Alzheimer’s disease suppress VE-cadherin expression and induce barrier dysfunction in recipient brain microvascular endothelial cell.” Journal of Alzheimer’s Disease (2023).<\/p>\n\n\n\n

Bei, J., Qiu, Y., Cockrell, D., Chang, Q., Husseinzadeh, S., Zhou, C., Fang, X., Bao, X., Jin, Y., Gaitas, A., Khanipov, K. “Identification of common sequence motifs shared exclusively among selectively packed exosomal pathogenic microRNAs during rickettsial infections.” Journal of Cellular Physiology (2023).<\/p>\n\n\n\n

Zijun Zhang; Natalie Sauerwald; Antonio Cappuccio; Irene Ramos; Venugopalan D. Nair; German Nudelman; Elena Zaslavsky; Yongchao Ge; Angelo Gaitas; Hui Ren; Joel Brockman; Jennifer Geis; Naveen Ramalingam; David King; Micah T. McClain; Christopher W. Woods; Ricardo Henao; Thomas W. Burke; Ephraim L. Tsalik; Carl W. Goforth; Rhonda A. Lizewski; Stephen E. Lizewski; Dawn L. Weir; Andrew G. Letizia; Stuart C. Sealfon; Olga G. Troyanskaya. “Blood RNA alternative splicing events as novel diagnostic biomarkers for infectious disease.” Cell Reports Methods (2023).<\/p>\n\n\n\n

Torres, I., Aghaei, S.M., Pala, N. and Gaitas, A. “Selective area multilayer graphene synthesis using resistive nanoheater probe.” Scientific Reports 13(1), p.7976 (2023).<\/p>\n\n\n\n

Mondal, M., J. Gacha-Garay, K. Larkin, R. Adikes, J. Di Martino, C. C. Chien, M. Fraser, I. Eniaganga, E. Agullo-Pascual, U. Ozbek, A. Naba, A. Gaitas, T. M. Fu, S. Upadhyayula, E. Betzig, D. Matus, B. L. Martin, J. J. Bravo-Cordero. “A Proliferative to Invasive Switch is Mediated by srGAP1 Downregulation Through the Activation of TGF\u03b22 Signaling.” Cell Reports (2022).<\/p>\n\n\n\n

Qiu, Yuan, Chen-Chi Chien, Basile Maroulis, Jiani Bei, Angelo Gaitas, and Bin Gong. “Extending applications of AFM to fluidic AFM in single living cell studies.” Journal of Cellular Physiology (2022).<\/p>\n\n\n\n

Zhou Changcheng, Bei Jiani, Qiu Yuan, Chang Qing, Nyong Emmanuel, Vasilakis Nikos, Yang Jun, Krishnan Balaji, Khanipov Kamil, Jin Yang, Fang Xiang, Gaitas Angelo, Gong Bin. “Exosomally Targeting microRNA23a Ameliorates Microvascular Endothelial Barrier Dysfunction Following Rickettsial Infection.” Frontiers in Immunology (2022).<\/p>\n\n\n\n

C. Chien, J. Jiang, B. Gong, T. Li, A. Gaitas. “AFM Microfluidic Cantilevers as Weight Sensors for Single Cell Mass Measurements.” Measurement Science and Technology (2022).<\/p>\n\n\n\n

Xiao, J., Zhang, B., Su, Z., Liu, Y., Shelite, T.R., Chang, Q., Qiu, Y., Bei, J., Wang, P., Bukreyev, A., Soong, L., Jin, Y., Ksiazek, T., Gaitas, A., Rossi, S.L., Zhou, J., Laposata, M., Saito, T.B., Gong, B. “Intracellular receptor EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K-\/eNOS-dependent manner during inflammation.” Journal of Biological Chemistry 297(5) (2021).<\/p>\n\n\n\n

Y. Liu, C. Zhou, Z. Su, Q. Chang, Y. Qiu, J. Bei, A. Gaitas et al. “Endothelial Exosome Plays a Functional Role During Rickettsial Infection.” mBio 12(3), e00769-21 (2021).<\/p>\n\n\n\n

C. Turnbull, W. Zhu, F. Stillitano, C. C. Chien, A. Gaitas. “A Micromachined Force Sensing Apparatus and Method for Human Engineered Cardiac Tissue and Induced Pluripotent Stem Cell Characterization.” Sensors and Actuators A: Physical, 112874 (2021).<\/p>\n\n\n\n

Su, Z., Shelite, T. R., Qiu, Y., Chang, Q., Wakamiya, M., Bei, J., He, X., Zhou, C., Liu, Y., Nyong, E., Liang, Y., Gaitas, A., Saito, T. B., & Gong, B. “Host EPAC Regulates Rickettsial Adhesion to Vascular Endothelial Cells via Regulation of ANXA2 Y23 Phosphorylation.” Pathogens (Basel, Switzerland) 10(10), 1307 (2021).<\/p>\n\n\n\n

X. He, W. Zhang, Q. Chang, Z. Su, D. Gong, Y. Zhou, J. Xiao, A. Drelich, Y. Liu, V. Popov, X. Zhao, M. Wakamiya, A. Gaitas, F. Lu, B. Gong. “A New Role for Host Annexin A2 in Establishing Bacterial Adhesion to Vascular Endothelial Cells.” Laboratory Investigation 99(11), 1650-1660 (2019).<\/p>\n\n\n\n

X. He, A. Drelich, S. Yu, Q. Chang, D. Gong, Y. Zhou, Y. Qu, Y. Yuan, Z. Su, Y. Qiu, S. J. Tang, A. Gaitas, T. Ksiazek, Z. Xu, J. Zhou, Z. Feng, M. Wakamiya, F. Lu, B. Gong. “Exchange Protein Directly Activated by cAMP Plays a Critical Role in Regulation of Vascular Fibrinolysis.” Life Sciences 15(221), 1-2 (2019).<\/p>\n\n\n\n

G. Kim, M. Karbaschi, M. Cooke, A. Gaitas. “Light-Based Methods for Whole Blood Bacterial Inactivation Enabled by a Recirculating Flow System.” Photochemistry and Photobiology 94(4), 744-751 (2018).<\/p>\n\n\n\n

G. Kim, H. Vinerean, A. Gaitas. “A Novel Pathogen Capturing Device for Removal and Detection.” Scientific Reports 7, 1-11 (2017).<\/p>\n\n\n\n

A. Gaitas, R. Malhotra, T. Li, T. Herron, J. Jalife. “A Device for Rapid and Quantitative Measurement of Cardiac Myocyte Contractility.” Review of Scientific Instruments 86(3), 034302 (2015).<\/p>\n\n\n\n

A. Gaitas, G. Kim. “Chemically Modified Plastic Tube for High Volume Removal and Collection of Circulating Tumor Cells.” PLoS One 10(7) (2015).<\/p>\n\n\n\n

G. Kim, A. Gaitas. “Extracorporeal Photo-Immunotherapy for Circulating Tumor Cells.” PLoS One 10(5) (2015).<\/p>\n\n\n\n

A. Gaitas, G. Kim. “Inductive Heating Kills Cells that Contribute to Plaque: A Proof-of-Concept.” PeerJ 3, e929 (2015).<\/p>\n\n\n\n

A. Gaitas, R. W. Hower. “SU-8 Microcantilever With an Aperture, Fluidic Channel, and Sensing Mechanisms for Biological and Other Applications.” Journal of Micro\/Nanolithography, MEMS, and MOEMS 13(3), 030501 (2014).<\/p>\n\n\n\n

A. Gaitas, B. H. McNaughton. “Nickel Foil Microcantilevers for Magnetic Manipulation and Localized Heating.” Sensor Letters 11(12), 2341-2344 (2013).<\/p>\n\n\n\n

A. Gaitas, R. Malhotra, K. Pienta. “A Method to Measure Cellular Adhesion Utilizing a Polymer Micro-Cantilever.” Applied Physics Letters 103(12), 123702 (2013).<\/p>\n\n\n\n

A. Gaitas. “Tip-Based Chemical Vapor Deposition with a Scanning Nano-Heater.” Applied Physics Letters 102(13), 133104 (2013).<\/p>\n\n\n\n

A. Gaitas, S. Wolgast, E. Covington, C. Kurdak. “Hot-Spot Detection and Calibration of a Scanning Thermal Probe with a Noise Thermometry Gold Wire Sample.” Journal of Applied Physics 113(7), 074304 (2013).<\/p>\n\n\n\n

A. Gaitas, P. French. “Piezo-Thermal Probe Array for High Throughput Applications.” Sensors and Actuators A: Physical 186, 125-129 (2012).<\/p>\n\n\n\n

W. Zhu, J. Park, J. L. Sessler, A. Gaitas. “A Colorimetric Receptor Combined with a Microcantilever Sensor for Explosive Vapor Detection.” Applied Physics Letters 98, 123501 (2011).<\/p>\n\n\n\n

Gaitas, T. Li, W. Zhu. “A Probe with Ultrathin Metal Piezoresistive Sensor for Scanning Probe Microscopy and Material Characterization.” Sensors & Actuators 168(2) (2011).<\/p>\n\n\n\n

Gaitas, S. Gianchandani, W. Zhu. “A Piezo-Thermal Probe for Thermomechanical Analysis.” Review of Scientific Instruments 82, 053701 (2011).<\/p>\n\n\n\n

Gaitas, W. Zhu, N. Gulari, E. Covington, C. Kurdak. “Characterization of Room Temperature Metal Microbolometers near the Metal-Insulator Transition Regime for Scanning Thermal Microscopy.” Applied Physics Letters 95(15), 153108 (2009).<\/p>\n\n\n\n

Mitra, A. Gaitas. “Thermally Actuated Tapping Mode Atomic Force Microscopy with Polymer Microcantilevers.” Review of Scientific Instruments 80, 023703 (2009).<\/p>\n\n\n\n

Gaitas. “A Preliminary Study of Spatial Resolution Enhancement of Confocal and Triangulation Displacement Meters Using Contact Mode Scanning Probes.” Review of Scientific Instruments 79, 023703 (2008).<\/p>\n\n\n\n

Gaitas, Y. Gianchandani. “An Experimental Study of Contact Mode Scan Speed Constraints for Polyimide Cantilever Probes.” Ultramicroscopy 106(8-9) (2006).<\/p>\n\n\n\n

Gaitas. “Polyimide Probes for Contact Mode Subsurface SPM Thermal Imaging.” Microscopy & Analysis 20(2) (2006).<\/p>\n\n\n\n

<\/p>\n\n\n\n

Preprints<\/strong><\/h2>\n\n\n\n

R. Gillette, I. C. Turnbull, V. D. Nair, and A. Gaitas, “Preliminary insights into the acute molecular responses in C2C12 myotubes to hyperthermia and insulin treatment,” bioRxiv, 2025, preprint 2025.03.26.644592.<\/p>\n\n\n\n

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  1. <\/li>\n<\/ol>\n\n\n\n

    <\/p>\n\n\n\n

    Conference Papers<\/strong><\/h2>\n\n\n\n

    V. Patel, O. Srivannavit, and A. Gaitas. “MEMS thermocouple microneedle reveals localized thermogenesis during high-frequency synaptic activity in hippocampal CA1,” in Technical Digest, Hilton Head Workshop 2026: A Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head Island, South Carolina, United States, May 31-June 4, 2026.<\/p>\n\n\n\n

    Jiani Bei, Yuan Qiu, Chandramouli Natarajan, Michelle Felicella, Balaji Krishnan, Angelo Gaitas, Xiang Fang, Bin Gong. “Alzheimer’s disease circulating-exosomes are proinflammatory in recipient brain microvascular endothelial cell in an RNA-cargo-dependent manner,” Neuroscience 2022 (2022).<\/p>\n\n\n\n

    T. Ingrid, S. M. Aghaei, N. Pala, A. Gaitas. “In-Situ Synthesis of Multilayer Graphene on Tin Film via Localized Heating of Amorphous Carbon Using an Electrothermal Cantilever Nanoprobe.” 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) (2021).<\/p>\n\n\n\n

    S. Wolgast, C. Kurdak, A. Gaitas, W. Zhu. “Measuring Transport Properties of Thin Films Under Isotropic and Anisotropic Strain Using Piezoelectric Substrates.” APS Meeting Abstracts (2011).<\/p>\n\n\n\n

    A. Gaitas, P. French. “Piezoresistive Probe Array for High Throughput Applications.” Proceedings of Eurosensors XXV (2011).<\/p>\n\n\n\n

    K. Lai, A. Gaitas, N. Xi, R. Yang, C. K. M. Fung. “Development and Testing of Nano Robot End Effector for Cell Electrophysiology and Elastography Studies.” Proceedings of the IEEE NANO 2011 (2011).<\/p>\n\n\n\n

    A. Gaitas, P. French. “Magnetic Microheaters for Cell Separation, Manipulation, & Lysis.” 16th International Conference on Solid-State Sensors, Actuators and Microsystems (2011).<\/p>\n\n\n\n

    S. Wolgast, C. Kurdak, A. Gaitas, W. Zhu. “Measuring Transport Properties of Thin Films, Under Isotropic and Anisotropic Strain Using Piezoelectric Substrates.” APS, Vol. 56, No. 1 (2011).<\/p>\n\n\n\n

    K. Lai, A. Gaitas, R. Yang, C. K. M. Fung, N. Xi. “Ultra-compliant Thermal AFM Probes for Studying of Cellular Properties.” IEEE NANO (2010).<\/p>\n\n\n\n

    A. Gaitas, S. Xu. “High Resolution Scanning Thermal Microscopy Using Polymer Probes with Embedded Metal Thermistors.” The Seventh International Meeting on Scanning Probe Microscopy, Sensors & Nanostructures, Cancun, Mexico (2005).<\/p>\n\n\n\n

    A. Gaitas, Y. B. Gianchandani. “Polyimide Probes for Contact Mode High-Speed Atomic Force Microscopy Imaging.” The Seventh International Meeting on Scanning Probe Microscopy, Sensors & Nanostructures, Cancun, Mexico (2005).<\/p>\n\n\n\n

    <\/p>\n\n\n\n

    Issued Patents<\/strong><\/h2>\n\n\n\n

    PAT. NO. 15\/978,461 Direct and Selective Area Synthesis of Graphene Using Microheater Elements, A. Gaitas, N. Pala (2019), assigned to FIU.<\/p>\n\n\n\n

    PAT. NO. 13\/706,450 Polymeric Micro-Arm Apparatus and Method to Use the Same, A. Gaitas (2016).<\/p>\n\n\n\n

    PAT. NO. 8,897,856 Atherosclerosis Therapy Via Delivery and Localized Heating of Micro Size Particles, A. Gaitas (2014).<\/p>\n\n\n\n

    PAT. NO. 8,394,625 Lab-on-a-Pipette, A. Gaitas, A. Basu (2013).<\/p>\n\n\n\n

    PAT. NO. 8,326,838 Education Credentials Management Method and System, A. Gaitas (2012).<\/p>\n\n\n\n

    PAT. NO. 8,297,837 Metal and Semimetal Sensors Near the Metal Insulator Transition Regime, A. Gaitas (2012).<\/p>\n\n\n\n

    PAT. NO. 8,192,809 Scanning Probe Assisted Localized CNT Growth, A. Gaitas, B. Mitra, A. Basu, W. Zhu (2012).<\/p>\n\n\n\n

    PAT. NO. 8,156,568 Hybrid Contact Mode Scanning Cantilever System, A. Gaitas, Y. Gianchandani (2012).<\/p>\n\n\n\n

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    Peer-Reviewed Journal Articles Patel, Vishwendra, Onnop Srivannavit, Irene C. Turnbull, Robert Blitzer, and Angelo Gaitas. “Micromachined Thermocouple Microprobe for Real-Time Thermometry of Hippocampal Slices during High-Frequency Stimulation.” (2026, under review) Turnbull, Irene C., Tai De Li, Pedro Sanabria, Aimee Stablewski, … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":335,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-46","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/pages\/46","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/users\/335"}],"replies":[{"embeddable":true,"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/comments?post=46"}],"version-history":[{"count":2,"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/pages\/46\/revisions"}],"predecessor-version":[{"id":60,"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/pages\/46\/revisions\/60"}],"wp:attachment":[{"href":"https:\/\/coefs.charlotte.edu\/agaitas\/wp-json\/wp\/v2\/media?parent=46"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}